Cattle Drive Casserole is a hearty, flavorful dish packed with seasoned ground beef, melty cheddar cheese, and a biscuit base. It’s easy to make and ideal for a hungry family. With layers of bold Tex-Mex flavor, it’s perfect for a simple weeknight meal or a cozy weekend dinner.
1. Preheat the oven to 350°F (180°C) and lightly grease a 9×13-inch baking dish with cooking spray.
2. In a medium bowl, stir together the baking mix, milk, and oil. Spread the mixture evenly in the prepared dish and bake for 10 to 15 minutes, or until it starts to turn golden brown. Remove from the oven and set aside.
3. Heat 1 tablespoon of oil in a large skillet over medium-high heat. Add the ground beef and cook, stirring occasionally, until almost cooked through with a bit of pink remaining, about 5 minutes.
4. Add the onion and red bell pepper, and cook, stirring occasionally and breaking the beef into small pieces, until the beef is fully cooked and the onions soften, about 3 minutes.
5. Stir in the taco seasoning and salt, and remove from heat. Set aside.
6. In a medium bowl, mix together the mayonnaise, sour cream, and 1 cup each of pepper jack and cheddar cheese. Set aside.
7. Spoon the beef mixture evenly over the par-baked biscuit in the baking dish.
8. Top with the drained diced tomatoes and green chiles, followed by the mayonnaise mixture. Gently spread to cover, then sprinkle with the remaining cheese.
9. Bake for about 30 minutes, or until the casserole is bubbly and the cheese is melted and starting to brown.
10. Remove from the oven and let it rest for 10 minutes before serving.
Protein swaps: Use ground turkey, chicken, or even black beans for a meatless version.
Extra spice: Add chopped jalapeños or use spicy taco seasoning for a kick.
Cheese choices: Sharp cheddar, pepper jack, or a Mexican blend work well.
Make-ahead: Prepare the casserole up to a day in advance and bake when ready.
Drain excess grease: If your beef releases too much fat, drain it before adding the seasoning.
Store-bought biscuit dough: You can use pre-packaged biscuit dough if you prefer. Just pre-bake it slightly before adding the beef mixture.
Storage: Store leftovers in the fridge for up to 3 days or freeze for up to 3 months.
Reheat: Warm in the oven at 350°F (180°C) or microwave until heated through.
Find it online: https://cookingwithramsay.com/cattle-drive-casserole/